Nitrates come as tablets, sublingual under the tongue tablets, sprays, patches, pastes, and ointments. Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine. It may be taken with or without food. There are two different ways to take tadalafil, either daily or on an as needed basis. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. Your doctor will probably tell you not to take tadalafil if you are taking street drugs containing nitrates. Do not take more or less of it or take it more often than prescribed by your doctor.Best for insurance coverage. Cialis: available in doses of 5, 10, and 20 mg, starting at $65 per tablet. Daily Cialis: 5 mg tablet with pricing starting from $50 per tablet. Tadalafil: 20 mg tablet starting at $2 per tablet and higher doses starting at $25 per tablet. Tadalafil oral tablet is available as a generic drug and as brand-name drugs. Brand names: Cialis, Adcirca. Tadalafil comes only as a tablet you take by mouth. $ medication_outlined Availability Available See GoodRx coupons warning Are you looking for information on Adcirca (tadalafil) instead? What is Tadalafil (Cialis)? Drug Facts Common Brands Cialis Drug Class PDE-5 inhibitor Controlled Substance Classification Not a controlled medication Generic Status No lower-cost .