Persons surnamed “Cialis” objected to Eli Lilly and Company’s so naming the drug, but the company has maintained that the drug’s trade name is unrelated to the surname. Read more on male sexual health on the Sexual Health Australia site. Cialis Regular will have a higher dosage and is not designed for daily or regular use. In , the Phase 2 clinical studies were initiated for males experiencing ED, then progressed to the Phase 3 trials that supported the drug’s FDA approval. Tadalafil can be synthesized starting from D – tryptophan methyl ester and piperonal via a Pictet—Spengler reaction. Benign prostatic hypertrophy is a condition in which the prostate gland becomes enlarged, obstructing the free flow of urine. Comparison with actions of other PDE5 inhibitors[ edit ] Sildenafil and vardenafil inhibit PDE6, an enzyme found in the eye, more than tadalafil.$ (save %) local_offer_outlined Avg retail price $ medication_outlined Availability Available See GoodRx coupons warning Are you looking for information on Adcirca (tadalafil) instead? What is Tadalafil (Cialis)? Drug Facts Common Brands Cialis Drug Class PDE-5 inhibitor. You can buy tadalafil at the discounted price of $ by using the MDRx coupon, a savings of 93%. Even if this drug is covered by Medicare or your insurance, we recommend you compare prices. The recommended starting dose for Cialis intended for once daily use is mg, take at the same time each day, without regard to timing of sexual activity. This may be increased to 5mg/day based on need and tolerability. May be taken with or without food. Cialis is available as a generic, under the name tadalafil. 3.