This helps to maintain an erection. If you feel the tablets are too strong for you, discuss this with your doctor as your dose may need to be reduced. Headache Drink plenty of water. You may take this medicine with or without food. Severe liver disease. An inherited eye disease that affects the retina. Dosing The dose of this medicine will be different for different patients. · By controlling the enzyme, avanafil helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. Without physical action to the . AdGet a Prescription for ED treatment, discreetly deliverED to your ive Offers · How It Works · Get More InfoService Catalog: P.E. Treatments, GET MORE INFO, Terms & Conditions, Instagram and more.  · This medicine usually begins to work within 60 minutes after taking it and stimulation of the penis is required. If you have any questions about the use of .