When oral medications might not be safe Check with your health care team before you take any medicine for erectile dysfunction. Should I see a specialist? You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. Exercise can help with underlying conditions that play a part in erectile dysfunction in a number of ways, including reducing stress, helping you lose weight and increasing blood flow. Your partner can help you remember something that you missed or forgot during the appointment.Sildenafil works similarly to Viagra but is available at a much lower price. It should be taken as needed, approximately 30–60 minutes before sexual activity, and it shouldn’t be taken more.  · How much do generic ED medications cost? Even without insurance, the average cost for a 25 mg dose of generic sildenafil costs between $16 to $30 for 30 tablets by using a coupon at retail pharmacies. Oral medications are a successful erectile dysfunction treatment for many men. They include: Sildenafil (Viagra) Tadalafil (Adcirca, Cialis) Vardenafil (Levitra, Staxyn) Avanafil (Stendra) All four medications enhance the effects of nitric oxide — a natural chemical your body produces that relaxes muscles in the penis.