Tadalafil and Cialis have identical results in clinical trials for their effectiveness. That said, some men have reported the effects kicking in after just 15 minutes! Over a weekend away, that would mean potentially as little as 30 minutes of waiting time for a stronger erection. Both start from about half an hour after you take them, which means no long delays before you get down to business. What varies between them is the dosage, bioavailability, the length of time their effect takes to kick in, the amount of time they last for, and the side effect profiles. In fact, the mixture of the two — alcohol and Cialis — can cause a dangerous drop in blood pressure.Cialis is often called the “weekend pill” as it’s effects can last up to 36 hours, meaning your sex life can have a certain amount of sponteneity not possible with other . Cialis is a popular ED medication. Find out everything you need to know about this doctor-prescribed medication including usage, effectiveness, and safety . Cialis (tadalafil) is an oral medication that treats erectile dysfunction (ED). One dose of Cialis lasts longer than a dose of the well-known Viagra (sildenafil). You .