Without physical action to the penis, such as that occurring during sexual intercourse, tadalafil will not work to cause an erection. Cialis was also investigated in combination with finasteride, another BPH medication, in another trial. Click here for an email preview. Armed with information tailored to your specific health condition ensures you reap maximum benefits while minimizing potential risks. Tadalafil was approved in in the United States for the treatment of pulmonary arterial hypertension [28] and is under regulatory review in other regions for this condition. However, because sexual stimulation is required to initiate the local penile release of nitric oxide, tadalafil’s inhibition of PDE5 will have no effect without sexual stimulation.Cialis (tadalafil) is a popular medication used to treat erectile dysfunction. It’s available in tablets ranging from mg to 20mg. It can cost more than $ for a month’s supply, depending on the dosage you need and the pharmacy you visit. You can save more than 90% on the average retail price at certain pharmacies by using a GoodRx coupon.  · Descriptions. Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence). Tadalafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where . Refill and transfer prescriptions online or find a CVS Pharmacy near you. Shop online, see ExtraCare deals, find MinuteClinic locations and more.