Your doctor will tell you not to take sildenafil if you are taking street drugs containing nitrates. This medicine is available on prescription and you can also buy it from most pharmacies. Especially tell your healthcare provider if you take any of the following: medicines called nitrates medicines called guanylate cyclase stimulators such as Adempas riociguat medicines called alpha-blockers, such as Hytrin terazosin HCl , Flomax tamsulosin HCl , Cardura doxazosin mesylate , Minipress prazosin HCl , Uroxatral alfuzosin HCl , Jalyn dutasteride and tamsulosin HCl , or Rapaflo silodosin. If you often forget doses, it may help to set an alarm to remind you. How to take tablets Swallow tablets whole with a drink of water or juice but not grapefruit juice.Sildenafil tablets for erectile dysfunction come in different strengths ranging from 25mg to mg. The usual dose is 50mg, when you need it. Do not take it more than once a day. The dose can be increased to mg or decreased to 25mg depending on its effect. Take sildenafil up to 4 hours before you want to have sex. Typical dosing for Sildenafil (Viagra) The typical dose is to take 50 mg of sildenafil (Viagra) by mouth, about 1 hour before sex, as needed. The maximum recommended dose is mg. Don’t take sildenafil (Viagra) more than once daily (at any dose). Written by Brian Leonard, PharmD, BCACP, BCGP. Extra 15% off $30 sitewide with code SAVE15; Clip your mystery deal! BOGO 50% off select Walgreens health & wellness.