Tadalafil works for these conditions by promoting muscle relaxation, which improves blood flow in PAH and urinary flow in BPH. Alternatively, Cialis may be prescribed as an as-needed treatment for ED, to be taken before sexual activity. Take tadalafil at around the same time every day. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry. Obesity Additionally, certain risk factors increase the risk of ED, such as smoking , lack of exercise, and drug or alcohol use. Tadalafil is also sometimes taken once a day every day without regard to timing of sexual activity.Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men. Tadalafil (Adcirca, Alyq) is an expensive drug used to treat pulmonary arterial drug is less popular than comparable drugs. It is available in both brand and generic versions. Generic tadalafil is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Typical dose: The typical starting dose is one 50 mg tablet. If you’re getting side effects, it can be cut down to 25 mg. If it’s not fully working, it can be increased to mg. Cialis (tadalafil) Cialis stands out by lasting longer than any of the other ED medications. It can also be taken on a daily basis.