However, because sexual stimulation is required to initiate the local penile release of nitric oxide, tadalafil’s inhibition of PDE5 will have no effect without sexual stimulation. People who are taking Cialis Tadalafil for erectile dysfunction may be able to continue taking alpha blockers. Cialis can last in the system for up to 36 hours. Daily use of Cialis Tadalafil is not recommended. Always keep medications out of reach of children and pets. And as the digital age continues to expand, staying informed is the best way to ensure you benefit from the convenience without compromising on safety. Heart conditions: Speak to your doctor before taking any medication for erectile dysfunction if you: have or have had heart disease have had a heart attack have had a stroke have angina chest pain as a result of poor blood flow to the heart muscle have experienced chest pain during sexual activity have uncontrolled irregular heart rhythm have very Low Blood Pressure have uncontrolled high blood pressure If you experience chest pains, dizziness, or nausea during sex, stop the exertion, and inform your doctor as soon as you can.Tadalafil, or generic Cialis, is most commonly used to treat erectile dysfunction (ED). However, it’s also used to treat benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension. CIALIS VIAGRA. Toll Free Phone: Toll Free Fax: 24 hours / 7 days a week. dispenses medications through our affiliated Canadian dispensing pharmacy which is licensed in the province of Manitoba, Canada. Cialis lasts up to 36 hours in the body, while Viagra lasts 4–6 hours in the body. Both are taken 30 minutes before sex. Cialis can cause limb pain, while Viagra can cause vision change, rash.