Your doctor may need to change the doses of your medications or monitor you carefully for side effects. They will also give medicines like Tadalafil a strong base to build upon. What special dietary instructions should I follow? Tadalafil is sometimes taken as needed, usually at least 30 minutes before sexual activity and not more often than once every 24 hours. All of these Phosphodiesterase 5 inhibitors work in a similar way: the relaxation of the penile blood vessels to support expansion, which gives a stronger erection during arousal. Sooner or later, all kisses, hugs and declarations of love will lead to intimacy.The recommended starting dose of CIALIS for use as needed in most patients is 10 mg, taken prior to anticipated sexual activity. The dose may be increased . Take tadalafil (Cialis) as prescribed by your provider. If you’re taking tadalafil (Cialis) as-needed for ED, you should take no more than one dose per day. The effects Author: Goodrx. Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged .